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Effects of STAT3 Gene Silencing and Rapamycin on Apoptosis in Hepatocarcinoma Cells

The PI3K/Akt/mTOR and JAK/STAT3 signaling pathways are important for regulating apoptosis, and are frequently activated in cancers. In this study, we targeted STAT3 and mTOR in human hepatocellular carcinoma Bel-7402 cells and examined the subsequent alterations in cellular apoptosis. The expression...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Zhang, Jun-Wei, Lv, Guo-Yue, Xie, Shu-Li, Wang, Guang-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298013/
https://www.ncbi.nlm.nih.gov/pubmed/22408571
http://dx.doi.org/10.7150/ijms.4004