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The Evolution of Pepsinogen C Genes in Vertebrates: Duplication, Loss and Functional Diversification

BACKGROUND: Aspartic proteases comprise a large group of enzymes involved in peptide proteolysis. This collection includes prominent enzymes globally categorized as pepsins, which are derived from pepsinogen precursors. Pepsins are involved in gastric digestion, a hallmark of vertebrate physiology....

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Detalles Bibliográficos
Autores principales: Castro, Luís Filipe Costa, Lopes-Marques, Monica, Gonçalves, Odete, Wilson, Jonathan Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298455/
https://www.ncbi.nlm.nih.gov/pubmed/22427897
http://dx.doi.org/10.1371/journal.pone.0032852