Japanese encephalitis virus induces matrix metalloproteinase-9 expression via a ROS/c-Src/PDGFR/PI3K/Akt/MAPKs-dependent AP-1 pathway in rat brain astrocytes

BACKGROUND: Japanese encephalitis virus (JEV) infection is a major cause of acute encephalopathy in children, which destroys central nervous system (CNS) cells, including astrocytes and neurons. Matrix metalloproteinase (MMP)-9 has been shown to degrade components of the basal lamina, leading to dis...

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Detalles Bibliográficos
Autores principales: Yang, Chuen-Mao, Lin, Chih-Chung, Lee, I-Ta, Lin, Yi-Hsin, Yang, Caleb M, Chen, Wei-June, Jou, Mei-Jie, Hsiao, Li-Der
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298505/
https://www.ncbi.nlm.nih.gov/pubmed/22251375
http://dx.doi.org/10.1186/1742-2094-9-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298505/
https://www.ncbi.nlm.nih.gov/pubmed/22251375
http://dx.doi.org/10.1186/1742-2094-9-12

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