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Down-regulation of the transcription factor snail in the placentas of patients with preeclampsia and in a rat model of preeclampsia

BACKGROUND: Placental malfunction in preeclampsia is believed to be a consequence of aberrant differentiation of trophoblast lineages and changes in utero-placental oxygenation. The transcription factor Snail, a master regulator molecule of epithelial-mesenchymal transition in embryonic development...

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Detalles Bibliográficos
Autores principales: Fedorova, Larisa, Gatto-Weis, Cara, Smaili, Sleiman, Khurshid, Nauman, Shapiro, Joseph I, Malhotra, Deepak, Horrigan, Terrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298516/
https://www.ncbi.nlm.nih.gov/pubmed/22360878
http://dx.doi.org/10.1186/1477-7827-10-15