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Down-regulation of the transcription factor snail in the placentas of patients with preeclampsia and in a rat model of preeclampsia
BACKGROUND: Placental malfunction in preeclampsia is believed to be a consequence of aberrant differentiation of trophoblast lineages and changes in utero-placental oxygenation. The transcription factor Snail, a master regulator molecule of epithelial-mesenchymal transition in embryonic development...
Autores principales: | Fedorova, Larisa, Gatto-Weis, Cara, Smaili, Sleiman, Khurshid, Nauman, Shapiro, Joseph I, Malhotra, Deepak, Horrigan, Terrence |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298516/ https://www.ncbi.nlm.nih.gov/pubmed/22360878 http://dx.doi.org/10.1186/1477-7827-10-15 |
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