TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation

BACKGROUND: Chronic neuroinflammation is a hallmark of several neurological disorders associated with cognitive loss. Activated microglia and secreted factors such as tumor necrosis factor (TNF)-α are key mediators of neuroinflammation and may contribute to neuronal dysfunction. Our study was aimed...

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Detalles Bibliográficos
Autores principales: Belarbi, Karim, Jopson, Timothy, Tweedie, David, Arellano, Carla, Luo, Weiming, Greig, Nigel H, Rosi, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298520/
https://www.ncbi.nlm.nih.gov/pubmed/22277195
http://dx.doi.org/10.1186/1742-2094-9-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298520/
https://www.ncbi.nlm.nih.gov/pubmed/22277195
http://dx.doi.org/10.1186/1742-2094-9-23

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