Cargando…

Genetic Background of Prop1(df) Mutants Provides Remarkable Protection Against Hypothyroidism-Induced Hearing Impairment

Hypothyroidism is a cause of genetic and environmentally induced deafness. The sensitivity of cochlear development and function to thyroid hormone (TH) mandates understanding TH action in this sensory organ. Prop1 (df) and Pou1f1 (dw) mutant mice carry mutations in different pituitary transcription...

Descripción completa

Detalles Bibliográficos
Autores principales: Fang, Qing, Giordimaina, Alicia M., Dolan, David F., Camper, Sally A., Mustapha, Mirna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298611/
https://www.ncbi.nlm.nih.gov/pubmed/22143287
http://dx.doi.org/10.1007/s10162-011-0302-3