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No impairment of monocyte-derived Langerhans cell phenotype or function in early-onset psoriasis

BACKGROUND: Migration of epidermal Langerhans cells (LCs) in response to the cytokines interleukin (IL)-1β and tumour necrosis factor (TNF)-α is impaired in uninvolved skin of patients with early-onset psoriasis. AIM: To investigate whether this impairment is a reflection of a systemic defect in den...

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Detalles Bibliográficos
Autores principales: Shaw, F L, Kimber, I, Begum, R, Cumberbatch, M, Dearman, R J, Griffiths, C E M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298657/
https://www.ncbi.nlm.nih.gov/pubmed/21933242
http://dx.doi.org/10.1111/j.1365-2230.2011.04172.x