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Dysfunction of the RAR/RXR signaling pathway in the forebrain impairs hippocampal memory and synaptic plasticity

BACKGROUND: Retinoid signaling pathways mediated by retinoic acid receptor (RAR)/retinoid × receptor (RXR)-mediated transcription play critical roles in hippocampal synaptic plasticity. Furthermore, recent studies have shown that treatment with retinoic acid alleviates age-related deficits in hippoc...

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Detalles Bibliográficos
Autores principales: Nomoto, Masanori, Takeda, Yohei, Uchida, Shusaku, Mitsuda, Koji, Enomoto, Hatsune, Saito, Kaori, Choi, Tesu, Watabe, Ayako M, Kobayashi, Shizuka, Masushige, Shoichi, Manabe, Toshiya, Kida, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298701/
https://www.ncbi.nlm.nih.gov/pubmed/22316320
http://dx.doi.org/10.1186/1756-6606-5-8