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GDNF protects enteric glia from apoptosis: evidence for an autocrine loop

BACKGROUND: Enteric glia cells (EGC) play an important role in the maintenance of intestinal mucosa integrity. During the course of acute Crohn's disease (CD), mucosal EGC progressively undergo apoptosis, though the mechanisms are largely unknown. We investigated the role of Glial-derived neuro...

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Detalles Bibliográficos
Autores principales: Steinkamp, Martin, Gundel, Heike, Schulte, Nadine, Spaniol, Ulrike, Pflueger, Carolin, Zizer, Eugen, von Boyen, Georg BT
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298702/
https://www.ncbi.nlm.nih.gov/pubmed/22251670
http://dx.doi.org/10.1186/1471-230X-12-6