Involvement of PPAR-γ in the neuroprotective and anti-inflammatory effects of angiotensin type 1 receptor inhibition: effects of the receptor antagonist telmisartan and receptor deletion in a mouse MPTP model of Parkinson's disease

BACKGROUND: Several recent studies have shown that angiotensin type 1 receptor (AT1) antagonists such as candesartan inhibit the microglial inflammatory response and dopaminergic cell loss in animal models of Parkinson's disease. However, the mechanisms involved in the neuroprotective and anti-...

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Detalles Bibliográficos
Autores principales: Garrido-Gil, Pablo, Joglar, Belen, Rodriguez-Perez, Ana I, Guerra, Maria J, Labandeira-Garcia, Jose L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298706/
https://www.ncbi.nlm.nih.gov/pubmed/22356806
http://dx.doi.org/10.1186/1742-2094-9-38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298706/
https://www.ncbi.nlm.nih.gov/pubmed/22356806
http://dx.doi.org/10.1186/1742-2094-9-38

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