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Pravastatin inhibits cell proliferation and increased MAT1A expression in hepatocarcinoma cells and in vivo models

BACKGROUND: Statins may have therapeutic effects on hepatocarcinoma (HCC). This type of disorder is the most common malignant primary tumour in the liver. Our objective was to determine whether pravastatin had a therapeutic effect in vitro and in vivo models. METHOD: We design in vitro and in vivo m...

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Detalles Bibliográficos
Autores principales: Hijona, Elizabeth, Banales, Jesús María, Hijona, Lander, Medina, Juan Francisco, Arenas, Juan, Herreros-Villanueva, Marta, Aldazabal, Pablo, Bujanda, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298718/
https://www.ncbi.nlm.nih.gov/pubmed/22353776
http://dx.doi.org/10.1186/1475-2867-12-5