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Discoidin domain receptors regulate the migration of primary human lung fibroblasts through collagen matrices
BACKGROUND: The two discoidin domain receptors (DDRs), DDR1 and DDR2 are receptor tyrosine kinases (RTKs) with the unique ability among RTKs to respond to collagen. We have previously shown that collagen I induces DDR1 and matrix metalloproteinase (MMP)-10 expression through DDR2 activation and a Ja...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298810/ https://www.ncbi.nlm.nih.gov/pubmed/22336030 http://dx.doi.org/10.1186/1755-1536-5-3 |