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Defective Mitochondrial Function and Motility Due to Mitofusin 1 Overexpression in Insulin Secreting Cells

Mitochondrial dynamics and distribution is critical for their role in bioenergetics and cell survival. We investigated the consequence of altered fission/fusion on mitochondrial function and motility in INS-1E rat clonal β-cells. Adenoviruses were used to induce doxycycline-dependent expression of w...

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Detalles Bibliográficos
Autores principales: Park, Kyu-Sang, Wiederkehr, Andreas, Wollheim, Claes B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298829/
https://www.ncbi.nlm.nih.gov/pubmed/22416223
http://dx.doi.org/10.4196/kjpp.2012.16.1.71