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Muscle gene electrotransfer is increased by the antioxidant tempol in mice

Electropermeabilization (EP) is an effective method of gene transfer into different tissues. During EP, reactive oxygen species (ROS) are formed, which could affect transfection efficiency. The role of generated ROS and the role of antioxidants in electrotransfer in myoblasts in vitro and in Musculu...

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Detalles Bibliográficos
Autores principales: Markelc, B, Tevz, G, Cemazar, M, Kranjc, S, Lavrencak, J, Zegura, B, Teissie, J, Sersa, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298856/
https://www.ncbi.nlm.nih.gov/pubmed/21716301
http://dx.doi.org/10.1038/gt.2011.97