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Specificity quantification of biomolecular recognition and its implication for drug discovery
Highly efficient and specific biomolecular recognition requires both affinity and specificity. Previous quantitative descriptions of biomolecular recognition were mostly driven by improving the affinity prediction, but lack of quantification of specificity. We developed a novel method SPA (SPecifici...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298884/ https://www.ncbi.nlm.nih.gov/pubmed/22413060 http://dx.doi.org/10.1038/srep00309 |