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Protection against SHIV-KB9 Infection by Combining rDNA and rFPV Vaccines Based on HIV Multiepitope and p24 Protein in Chinese Rhesus Macaques

Developing an effective vaccine against HIV infection remains an urgent goal. We used a DNA prime/fowlpox virus boost regimen to immunize Chinese rhesus macaques. The animals were challenged intramuscularly with pathogenic molecularly cloned SHIV-KB9. Immunogenicity and protective efficacy of vaccin...

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Detalles Bibliográficos
Autores principales: Li, Chang, Shen, Zhenwei, Li, Xiao, Bai, Jieying, Zeng, Lin, Tian, Mingyao, Song, Ying Jin, Ye, Ming, Du, Shouwen, Ren, Dayong, Liu, Cunxia, Zhu, Na, Sun, Dandan, Li, Yi, Jin, Ningyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299295/
https://www.ncbi.nlm.nih.gov/pubmed/22474488
http://dx.doi.org/10.1155/2012/958404