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(111)Indium Labelling of Recombinant Activated Coagulation Factor VII: In Vitro and Preliminary In Vivo Studies in Healthy Rats

The aim of this study is to investigate whether (111)Indium-labelled recombinant FVIIa (rFVIIa) could be a potential radiopharmaceutical for localization of bleeding sources. DTPA-conjugated rFVIIa was radiolabelled with (111)In chloride. In vitro binding efficiency of (111)In-DTPA-rFVIIa to F1A2-Ma...

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Detalles Bibliográficos
Autores principales: Nalla, Amarnadh, Buch, Inge, Sigvardt, Maibritt, Bodholdt, Rasmus Poul, Kjaer, Andreas, Hesse, Birger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299322/
https://www.ncbi.nlm.nih.gov/pubmed/22518302
http://dx.doi.org/10.1155/2012/464810