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Induction of Hemeoxygenase-1 Reduces Renal Oxidative Stress and Inflammation in Diabetic Spontaneously Hypertensive Rats

The renoprotective mechanisms of hemeoxygenase-1 (HO-1) in diabetic nephropathy remain to be investigated. We hypothesize that HO-1 protects the kidney from diabetic insult via lowering renal oxidative stress and inflammation. We used control and diabetic SHR with or without HO-1 inducer cobalt prot...

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Detalles Bibliográficos
Autores principales: Elmarakby, Ahmed A., Faulkner, Jessica, Baban, Babak, Sullivan, Jennifer C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299363/
https://www.ncbi.nlm.nih.gov/pubmed/22518298
http://dx.doi.org/10.1155/2012/957235