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Salt Bridges Regulate Both Dimer Formation and Monomeric Flexibility in HdeB and May Have a Role in Periplasmic Chaperone Function

Escherichia coli and Gram-negative bacteria that live in the human gut must be able to tolerate rapid and large changes in environmental pH. Low pH irreversibly denatures and precipitates many bacterial proteins. While cytoplasmic proteins are well buffered against such swings, periplasmic proteins...

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Detalles Bibliográficos
Autores principales: Wang, Wenjian, Rasmussen, Tim, Harding, Amanda J., Booth, Nuala A., Booth, Ian R., Naismith, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299563/
https://www.ncbi.nlm.nih.gov/pubmed/22138344
http://dx.doi.org/10.1016/j.jmb.2011.11.026