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Physiologically based pharmacokinetic modeling of PLGA nanoparticles with varied mPEG content

Biodistribution of nanoparticles is dependent on their physicochemical properties (such as size, surface charge, and surface hydrophilicity). Clear and systematic understanding of nanoparticle properties’ effects on their in vivo performance is of fundamental significance in nanoparticle design, dev...

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Detalles Bibliográficos
Autores principales: Li, Mingguang, Panagi, Zoi, Avgoustakis, Konstantinos, Reineke, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299578/
https://www.ncbi.nlm.nih.gov/pubmed/22419876
http://dx.doi.org/10.2147/IJN.S23758