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Physiologically based pharmacokinetic modeling of PLGA nanoparticles with varied mPEG content
Biodistribution of nanoparticles is dependent on their physicochemical properties (such as size, surface charge, and surface hydrophilicity). Clear and systematic understanding of nanoparticle properties’ effects on their in vivo performance is of fundamental significance in nanoparticle design, dev...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299578/ https://www.ncbi.nlm.nih.gov/pubmed/22419876 http://dx.doi.org/10.2147/IJN.S23758 |