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[(18)F]CFT synthesis and binding to monoamine transporters in rats

BACKGROUND: We present the electrophilic synthesis of [(18)F]2β-carbomethoxy-3β-(4-fluoro)tropane [[(18)F]CFT] and the pharmacological specificity and selectivity of [(18)F]CFT for monoamine transporters in the brain and peripheral organs of rats. The human radiation dose is extrapolated from the an...

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Detalles Bibliográficos
Autores principales: Forsback, Sarita, Marjamäki, Päivi, Eskola, Olli, Bergman, Jörgen, Rokka, Johanna, Grönroos, Tove, Haaparanta, Merja, Solin, Olof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299608/
https://www.ncbi.nlm.nih.gov/pubmed/22277306
http://dx.doi.org/10.1186/2191-219X-2-3