Cargando…

Estimating the mode of inheritance in genetic association studies of qualitative traits based on the degree of dominance index

BACKGROUND: The biological justification for the choice of the genetic mode in genetic association studies (GAS) is seldom available. Then, the mode of inheritance is approximated by investigating a number of non-orthogonal genetic contrasts making the interpretation of results difficult. METHODS: W...

Descripción completa

Detalles Bibliográficos
Autores principales: Zintzaras, Elias, Santos, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299619/
https://www.ncbi.nlm.nih.gov/pubmed/22188898
http://dx.doi.org/10.1186/1471-2288-11-171