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Estimating the mode of inheritance in genetic association studies of qualitative traits based on the degree of dominance index
BACKGROUND: The biological justification for the choice of the genetic mode in genetic association studies (GAS) is seldom available. Then, the mode of inheritance is approximated by investigating a number of non-orthogonal genetic contrasts making the interpretation of results difficult. METHODS: W...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299619/ https://www.ncbi.nlm.nih.gov/pubmed/22188898 http://dx.doi.org/10.1186/1471-2288-11-171 |