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Protein L: a novel reagent for the detection of Chimeric Antigen Receptor (CAR) expression by flow cytometry

BACKGROUND: There has been significant progress in the last two decades on the design of chimeric antigen receptors (CAR) for adoptive immunotherapy targeting tumor-associated antigens. Structurally CARs consist of a single chain antibody fragment directed against a tumor-associated antigen fused to...

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Detalles Bibliográficos
Autores principales: Zheng, Zhili, Chinnasamy, Nachimuthu, Morgan, Richard A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299624/
https://www.ncbi.nlm.nih.gov/pubmed/22330761
http://dx.doi.org/10.1186/1479-5876-10-29