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DNA Methylation-Independent Reversion of Gemcitabine Resistance by Hydralazine in Cervical Cancer Cells

BACKGROUND: Down regulation of genes coding for nucleoside transporters and drug metabolism responsible for uptake and metabolic activation of the nucleoside gemcitabine is related with acquired tumor resistance against this agent. Hydralazine has been shown to reverse doxorubicin resistance in a mo...

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Detalles Bibliográficos
Autores principales: Candelaria, Myrna, de la Cruz-Hernandez, Erick, Taja-Chayeb, Lucia, Perez-Cardenas, Enrique, Trejo-Becerril, Catalina, Gonzalez-Fierro, Aurora, Chavez-Blanco, Alma, Soto-Reyes, Ernesto, Dominguez, Guadalupe, Trujillo, Jaenai E., Diaz-Chavez, Jose, Duenas-Gonzalez, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299634/
https://www.ncbi.nlm.nih.gov/pubmed/22427797
http://dx.doi.org/10.1371/journal.pone.0029181