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DNA Methylation-Independent Reversion of Gemcitabine Resistance by Hydralazine in Cervical Cancer Cells
BACKGROUND: Down regulation of genes coding for nucleoside transporters and drug metabolism responsible for uptake and metabolic activation of the nucleoside gemcitabine is related with acquired tumor resistance against this agent. Hydralazine has been shown to reverse doxorubicin resistance in a mo...
Autores principales: | Candelaria, Myrna, de la Cruz-Hernandez, Erick, Taja-Chayeb, Lucia, Perez-Cardenas, Enrique, Trejo-Becerril, Catalina, Gonzalez-Fierro, Aurora, Chavez-Blanco, Alma, Soto-Reyes, Ernesto, Dominguez, Guadalupe, Trujillo, Jaenai E., Diaz-Chavez, Jose, Duenas-Gonzalez, Alfonso |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299634/ https://www.ncbi.nlm.nih.gov/pubmed/22427797 http://dx.doi.org/10.1371/journal.pone.0029181 |
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