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Invariant Natural Killer T Cell Agonist Modulates Experimental Focal and Segmental Glomerulosclerosis

A growing body of evidence demonstrates a correlation between Th2 cytokines and the development of focal and segmental glomerulosclerosis (FSGS). Therefore, we hypothesized that GSL-1, a monoglycosylceramide from Sphingomonas ssp. with pro-Th1 activity on invariant Natural Killer T (iNKT) lymphocyte...

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Detalles Bibliográficos
Autores principales: Pereira, Rafael L., Reis, Vanessa O., Semedo, Patricia, Buscariollo, Bruna N., Donizetti-Oliveira, Cassiano, Cenedeze, Marcos A., Soares, Maria Fernanda, Pacheco-Silva, Alvaro, Savage, Paul B., Câmara, Niels O. S., Keller, Alexandre C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299669/
https://www.ncbi.nlm.nih.gov/pubmed/22427838
http://dx.doi.org/10.1371/journal.pone.0032454