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Simulation and Mechanistic Investigation of the Arrhythmogenic Role of the Late Sodium Current in Human Heart Failure

Heart failure constitutes a major public health problem worldwide. The electrophysiological remodeling of failing hearts sets the stage for malignant arrhythmias, in which the role of the late Na(+) current (I(NaL)) is relevant and is currently under investigation. In this study we examined the role...

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Detalles Bibliográficos
Autores principales: Trenor, Beatriz, Cardona, Karen, Gomez, Juan F., Rajamani, Sridharan, Ferrero, Jose M., Belardinelli, Luiz, Saiz, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299678/
https://www.ncbi.nlm.nih.gov/pubmed/22427860
http://dx.doi.org/10.1371/journal.pone.0032659