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Simulation and Mechanistic Investigation of the Arrhythmogenic Role of the Late Sodium Current in Human Heart Failure
Heart failure constitutes a major public health problem worldwide. The electrophysiological remodeling of failing hearts sets the stage for malignant arrhythmias, in which the role of the late Na(+) current (I(NaL)) is relevant and is currently under investigation. In this study we examined the role...
Autores principales: | Trenor, Beatriz, Cardona, Karen, Gomez, Juan F., Rajamani, Sridharan, Ferrero, Jose M., Belardinelli, Luiz, Saiz, Javier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299678/ https://www.ncbi.nlm.nih.gov/pubmed/22427860 http://dx.doi.org/10.1371/journal.pone.0032659 |
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