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The Homeostatic Chemokine CCL21 Predicts Mortality and May Play a Pathogenic Role in Heart Failure

BACKGROUND: CCL19 and CCL21, acting through CCR7, are termed homeostatic chemokines. Based on their role in concerting immunological responses and their proposed involvement in tissue remodeling, we hypothesized that these chemokines could play a pathogenic role in heart failure (HF). METHODOLOGY/PR...

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Detalles Bibliográficos
Autores principales: Yndestad, Arne, Finsen, Alexandra Vanessa, Ueland, Thor, Husberg, Cathrine, Dahl, Christen P., Øie, Erik, Vinge, Leif Erik, Sjaastad, Ivar, Sandanger, Øystein, Ranheim, Trine, Dickstein, Kenneth, Kjekshus, John, Damås, Jan Kristian, Fiane, Arnt E., Hilfiker-Kleiner, Denise, Lipp, Martin, Gullestad, Lars, Christensen, Geir, Aukrust, Pål
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299722/
https://www.ncbi.nlm.nih.gov/pubmed/22427939
http://dx.doi.org/10.1371/journal.pone.0033038