In Vivo Depletion of Lymphotoxin-Alpha Expressing Lymphocytes Inhibits Xenogeneic Graft-versus-Host-Disease

Graft-versus-host disease (GVHD) is a major barrier to successful allogeneic hematopoietic cell transplantation and is largely mediated by activated donor lymphocytes. Lymphotoxin (LT)-α is expressed by subsets of activated T and B cells, and studies in preclinical models demonstrated that targeted...

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Detalles Bibliográficos
Autores principales: Chiang, Eugene Y., Kolumam, Ganesh, McCutcheon, Krista M., Young, Judy, Lin, Zhonghua, Balazs, Mercedesz, Grogan, Jane L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299734/
https://www.ncbi.nlm.nih.gov/pubmed/22427961
http://dx.doi.org/10.1371/journal.pone.0033106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299734/
https://www.ncbi.nlm.nih.gov/pubmed/22427961
http://dx.doi.org/10.1371/journal.pone.0033106

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