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Perilipin 2 (PLIN2)-Deficiency Does Not Increase Cholesterol-Induced Toxicity in Macrophages

Interventions on macrophages/foam cells to redirect intracellular cholesterol towards efflux pathways could become a very valuable addition to our therapeutic arsenal against atherosclerosis. However, certain manipulations of the cholesteryl ester cycle, such as the inhibition of ACAT1, an ER-reside...

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Detalles Bibliográficos
Autores principales: Son, Se-Hee, Goo, Young-Hwa, Chang, Benny H., Paul, Antoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299742/
https://www.ncbi.nlm.nih.gov/pubmed/22427949
http://dx.doi.org/10.1371/journal.pone.0033063