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Perilipin 2 (PLIN2)-Deficiency Does Not Increase Cholesterol-Induced Toxicity in Macrophages
Interventions on macrophages/foam cells to redirect intracellular cholesterol towards efflux pathways could become a very valuable addition to our therapeutic arsenal against atherosclerosis. However, certain manipulations of the cholesteryl ester cycle, such as the inhibition of ACAT1, an ER-reside...
Autores principales: | Son, Se-Hee, Goo, Young-Hwa, Chang, Benny H., Paul, Antoni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299742/ https://www.ncbi.nlm.nih.gov/pubmed/22427949 http://dx.doi.org/10.1371/journal.pone.0033063 |
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