Whole Exome Sequencing in a Random Sample of North American Women with Leiomyomas Identifies MED12 Mutations in Majority of Uterine Leiomyomas

Uterine leiomyomas (uterine fibroids) arise from smooth muscle tissue in the majority of women by age 45. It is common for these clonal tumors to develop from multiple locations within the uterus, leading to a variety of symptoms such as pelvic pain, abnormal uterine bleeding, and infertility. We pe...

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Detalles Bibliográficos
Autores principales: McGuire, Megan M., Yatsenko, Alexander, Hoffner, Lori, Jones, Mirka, Surti, Urvashi, Rajkovic, Aleksandar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299761/
https://www.ncbi.nlm.nih.gov/pubmed/22428002
http://dx.doi.org/10.1371/journal.pone.0033251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299761/
https://www.ncbi.nlm.nih.gov/pubmed/22428002
http://dx.doi.org/10.1371/journal.pone.0033251

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