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Increase in Muscle Mitochondrial Biogenesis Does Not Prevent Muscle Loss but Increased Tumor Size in a Mouse Model of Acute Cancer-Induced Cachexia

Cancer-associated cachexia is a complex metabolic condition characterized by the progressive loss of body fat and deterioration of muscle mass. Although the cellular and molecular mechanisms of cachexia are incompletely understood, previous studies have suggested mitochondrial dysfunction in murine...

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Detalles Bibliográficos
Autores principales: Wang, Xiao, Pickrell, Alicia M., Zimmers, Teresa A., Moraes, Carlos T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299794/
https://www.ncbi.nlm.nih.gov/pubmed/22428048
http://dx.doi.org/10.1371/journal.pone.0033426