Detection of PIGO-Deficient Cells Using Proaerolysin: A Valuable Tool to Investigate Mechanisms of Mutagenesis in the DT40 Cell System

While isogenic DT40 cell lines deficient in DNA repair pathways are a great tool to understand the DNA damage response to genotoxic agents by a comparison of cell toxicity in mutants and parental DT40 cells, no convenient mutation assay for mutagens currently exists for this reverse-genetic system....

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Detalles Bibliográficos
Autores principales: Nakamura, Jun, Gul, Husamettin, Tian, Xu, Bultman, Scott J., Swenberg, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299801/
https://www.ncbi.nlm.nih.gov/pubmed/22428069
http://dx.doi.org/10.1371/journal.pone.0033563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299801/
https://www.ncbi.nlm.nih.gov/pubmed/22428069
http://dx.doi.org/10.1371/journal.pone.0033563

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