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Suppression of Tumorigenicity-14, encoding matriptase, is a critical suppressor of colitis and colitis-associated colon carcinogenesis

Colitis-associated colorectal cancers are an etiologically distinct subgroup of colon cancers that occur in individuals suffering from inflammatory bowel disease and arise as a consequence of persistent exposure of hyperproliferative epithelial stem cells to an inflammatory microenvironment. An intr...

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Detalles Bibliográficos
Autores principales: Kosa, Peter, Szabo, Roman, Molinolo, Alfredo A., Bugge, Thomas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299858/
https://www.ncbi.nlm.nih.gov/pubmed/22139080
http://dx.doi.org/10.1038/onc.2011.545