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Suppression of Tumorigenicity-14, encoding matriptase, is a critical suppressor of colitis and colitis-associated colon carcinogenesis
Colitis-associated colorectal cancers are an etiologically distinct subgroup of colon cancers that occur in individuals suffering from inflammatory bowel disease and arise as a consequence of persistent exposure of hyperproliferative epithelial stem cells to an inflammatory microenvironment. An intr...
Autores principales: | Kosa, Peter, Szabo, Roman, Molinolo, Alfredo A., Bugge, Thomas H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299858/ https://www.ncbi.nlm.nih.gov/pubmed/22139080 http://dx.doi.org/10.1038/onc.2011.545 |
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