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Reducing agents affect inhibitory activities of compounds: Results from multiple drug targets
High-throughput screening (HTS) of large compound libraries has become a commonly used method for the identification of drug leads, and nonphysiological reducing agents have been widely used for HTS. However, a comparison of the difference in the HTS results based on the choice of reducing agent use...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299889/ https://www.ncbi.nlm.nih.gov/pubmed/22310499 http://dx.doi.org/10.1016/j.ab.2012.01.006 |