The Nuclear Receptor TR3 Regulates mTORC1 Signaling in Lung Cancer Cells Expressing Wild-type p53

The orphan nuclear receptor TR3 (NR41A, Nur77) is overexpressed in most lung cancer patients and is a negative prognostic factor for patient survival. The function of TR3 was investigated in non-small cell lung cancer A549 and H460 cells, and knockdown of TR3 by RNA interference (siTR3) inhibited ca...

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Detalles Bibliográficos
Autores principales: Lee, Syng-Ook, Andey, Terrick, Jin, Un-Ho, Kim, Kyounghyun, Sachdeva, Mandip, Safe, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299891/
https://www.ncbi.nlm.nih.gov/pubmed/22081070
http://dx.doi.org/10.1038/onc.2011.504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299891/
https://www.ncbi.nlm.nih.gov/pubmed/22081070
http://dx.doi.org/10.1038/onc.2011.504

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