Accuracy of BRCA1/2 Mutation Prediction Models for Different Ethnicities and Genders: Experience in a Southern Chinese Cohort

BACKGROUND: BRCA1/2 mutation prediction models (BRCAPRO, Myriad II, Couch, Shattuck-Eidens, BOADICEA) are well established in western cohorts to estimate the probability of BRCA1/2 mutations. Results are conflicting in Asian populations. Most studies did not account for gender-specific prediction. W...

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Detalles Bibliográficos
Autores principales: Kwong, Ava, Wong, Connie H. N., Suen, Dacita T. K., Co, Michael, Kurian, Allison W., West, Dee W., Ford, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299960/
https://www.ncbi.nlm.nih.gov/pubmed/22290208
http://dx.doi.org/10.1007/s00268-011-1406-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299960/
https://www.ncbi.nlm.nih.gov/pubmed/22290208
http://dx.doi.org/10.1007/s00268-011-1406-y

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