Fosmid-based whole genome haplotyping of a HapMap trio child: evaluation of Single Individual Haplotyping techniques

Determining the underlying haplotypes of individual human genomes is an essential, but currently difficult, step toward a complete understanding of genome function. Fosmid pool-based next-generation sequencing allows genome-wide generation of 40-kb haploid DNA segments, which can be phased into cont...

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Detalles Bibliográficos
Autores principales: Duitama, Jorge, McEwen, Gayle K., Huebsch, Thomas, Palczewski, Stefanie, Schulz, Sabrina, Verstrepen, Kevin, Suk, Eun-Kyung, Hoehe, Margret R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299995/
https://www.ncbi.nlm.nih.gov/pubmed/22102577
http://dx.doi.org/10.1093/nar/gkr1042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299995/
https://www.ncbi.nlm.nih.gov/pubmed/22102577
http://dx.doi.org/10.1093/nar/gkr1042

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