Maximizing signal-to-noise ratio in the random mutation capture assay

The ‘Random Mutation Capture’ assay allows for the sensitive quantitation of DNA mutations at extremely low mutation frequencies. This method is based on PCR detection of mutations that render the mutated target sequence resistant to restriction enzyme digestion. The original protocol prescribes an...

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Detalles Bibliográficos
Autores principales: Poovathingal, Suresh Kumar, Gruber, Jan, Ng, Li Fang, Halliwell, Barry, Gunawan, Rudiyanto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300001/
https://www.ncbi.nlm.nih.gov/pubmed/22180539
http://dx.doi.org/10.1093/nar/gkr1221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300001/
https://www.ncbi.nlm.nih.gov/pubmed/22180539
http://dx.doi.org/10.1093/nar/gkr1221

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