Specialization of an Exonuclease III family enzyme in the repair of 3′ DNA lesions during base excision repair in the human pathogen Neisseria meningitidis

We have previously demonstrated that the two Exonuclease III (Xth) family members present within the obligate human pathogen Neisseria meningitidis, NApe and NExo, are important for survival under conditions of oxidative stress. Of these, only NApe possesses AP endonuclease activity, while the prima...

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Detalles Bibliográficos
Autores principales: Silhan, Jan, Nagorska, Krzysztofa, Zhao, Qiyuan, Jensen, Kirsten, Freemont, Paul S., Tang, Christoph M., Baldwin, Geoff S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300015/
https://www.ncbi.nlm.nih.gov/pubmed/22067446
http://dx.doi.org/10.1093/nar/gkr905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300015/
https://www.ncbi.nlm.nih.gov/pubmed/22067446
http://dx.doi.org/10.1093/nar/gkr905

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