A flexible brace maintains the assembly of a hexameric replicative helicase during DNA unwinding

The mechanism of DNA translocation by papillomavirus E1 and polyomavirus LTag hexameric helicases involves consecutive remodelling of subunit–subunit interactions around the hexameric ring. Our biochemical analysis of E1 helicase demonstrates that a 26-residue C-terminal segment is critical for main...

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Detalles Bibliográficos
Autores principales: Whelan, Fiona, Stead, Jonathan A., Shkumatov, Alexander V., Svergun, Dmitri I., Sanders, Cyril M., Antson, Alfred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300016/
https://www.ncbi.nlm.nih.gov/pubmed/22067453
http://dx.doi.org/10.1093/nar/gkr906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300016/
https://www.ncbi.nlm.nih.gov/pubmed/22067453
http://dx.doi.org/10.1093/nar/gkr906

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