Cargando…

Direct, genome-wide assessment of DNA mutations in single cells

DNA mutations are the inevitable consequences of errors that arise during replication and repair of DNA damage. Because of their random and infrequent occurrence, quantification and characterization of DNA mutations in the genome of somatic cells has been difficult. Random, low-abundance mutations a...

Descripción completa

Detalles Bibliográficos
Autores principales: Gundry, Michael, Li, Wenge, Maqbool, Shahina Bano, Vijg, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300019/
https://www.ncbi.nlm.nih.gov/pubmed/22086961
http://dx.doi.org/10.1093/nar/gkr949