Enhancing the cellular uptake of Py–Im polyamides through next-generation aryl turns

Pyrrole–imidazole (Py–Im) hairpin polyamides are a class of programmable, sequence-specific DNA binding oligomers capable of disrupting protein–DNA interactions and modulating gene expression in living cells. Methods to control the cellular uptake and nuclear localization of these compounds are esse...

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Detalles Bibliográficos
Autores principales: Meier, Jordan L., Montgomery, David C., Dervan, Peter B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Synthetic Biology and Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300022/
https://www.ncbi.nlm.nih.gov/pubmed/22080545
http://dx.doi.org/10.1093/nar/gkr970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300022/
https://www.ncbi.nlm.nih.gov/pubmed/22080545
http://dx.doi.org/10.1093/nar/gkr970

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