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Enhancing the cellular uptake of Py–Im polyamides through next-generation aryl turns
Pyrrole–imidazole (Py–Im) hairpin polyamides are a class of programmable, sequence-specific DNA binding oligomers capable of disrupting protein–DNA interactions and modulating gene expression in living cells. Methods to control the cellular uptake and nuclear localization of these compounds are esse...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300022/ https://www.ncbi.nlm.nih.gov/pubmed/22080545 http://dx.doi.org/10.1093/nar/gkr970 |