Nonspaced inverted DNA repeats are preferential targets for homology-directed gene repair in mammalian cells

DNA repeats constitute potential sites for the nucleation of secondary structures such as hairpins and cruciforms. Studies performed mostly in bacteria and yeast showed that these noncanonical DNA structures are breakage-prone, making them candidate targets for cellular DNA repair pathways. Possible...

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Detalles Bibliográficos
Autores principales: Holkers, Maarten, de Vries, Antoine A. F., Gonçalves, Manuel A. F. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300023/
https://www.ncbi.nlm.nih.gov/pubmed/22080552
http://dx.doi.org/10.1093/nar/gkr976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300023/
https://www.ncbi.nlm.nih.gov/pubmed/22080552
http://dx.doi.org/10.1093/nar/gkr976

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